Macrovascular diabetic complications: clinical characteristics, diagnosis and management. Diabetes mellitus DM is an independent risk factor for coronary heart disease, stroke, peripheral arterial disease and heart failure, which are the main causes of death in these patients. Moreover, patients with DM and cardiovascular disease have a worse prognosis than nondiabetics, present lower short-term survival, higher risk of recurrence of the disease and a worse response to the treatments proposed. In the last decades, diagnostic and therapeutic progress had already shown benefits concerning cardiovascular risk reduction in these patients, but their absolute mortality risk is still twice that of non-diabetic patients.
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Macrovascular diabetic complications: clinical characteristics, diagnosis and management. Diabetes mellitus DM is an independent risk factor for coronary heart disease, stroke, peripheral arterial disease and heart failure, which are the main causes of death in these patients.
Moreover, patients with DM and cardiovascular disease have a worse prognosis than nondiabetics, present lower short-term survival, higher risk of recurrence of the disease and a worse response to the treatments proposed. In the last decades, diagnostic and therapeutic progress had already shown benefits concerning cardiovascular risk reduction in these patients, but their absolute mortality risk is still twice that of non-diabetic patients. Because of this, the adoption of intensive treatment, with strict cardiovascular risk factor control, is a priority.
The present study presents the main clinical characteristics and also the practical approach for screening, diagnosis and treatment of patients with diabetic macrovascular disease. Keywords: Diabetes mellitus; cardiovascular disease; coronary artery disease; risk factors; treatment; diagnosis.
Este dado determinou que o DM passasse a ser considerado como um "equivalente de DCV estabelecida" Idealmente, apenas aqueles com maior risco para desenvolver eventos cardiovasculares deveriam realizar o rastreamento. Acidente vascular cerebral estabelecido. Prevalence of micro and macroangiopatic chronic complications and their risk factors in the care of out patients with type 2 diabetes mellitus.
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Morbidity and Mortality of Diabetes With Surgery
Medwave se preocupa por su privacidad y la seguridad de sus datos personales. Palabras clave: diabetic nephropathy, microvascular complications, chronic renal disease physiopathology. Las complicaciones de la diabetes pueden ser macro y micro vasculares. Como palabras clave se utilizaron pathophyisiology, diabetic nephropathy, microvascular complications, advanced glycation end products, oxidative stress, aldose reductase, renineangiotensine aldosterone system, protein kinase c, inflammation citokines, growth factors, gene, epigenetic, miRNAs. Cuando estas condiciones se mantienen en el tiempo, producen tanto una hipertrofia glomerular como un aumento de la superficie del capilar glomerular. Figura 1. Chronic kidney disease is a common complication of diabetes.
Guía de Actualización en Diabetes