ANTRACICLINAS Y CARDIOTOXICIDAD PDF

Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. Acquired long QT syndrome results from secondary causes and can be caused by more than non-antiarrhythmic drugs. Cardiac arrest due to Torsades de pointes induced by drugs causing prolonged QT syndrome is a rare but potentially fatal event, even in hospitals. The case of a year-old patient diagnosed with non-Hodgkin lymphoma admitted to the hematology department of the Dr.

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Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. Acquired long QT syndrome results from secondary causes and can be caused by more than non-antiarrhythmic drugs.

Cardiac arrest due to Torsades de pointes induced by drugs causing prolonged QT syndrome is a rare but potentially fatal event, even in hospitals. The case of a year-old patient diagnosed with non-Hodgkin lymphoma admitted to the hematology department of the Dr. View PDF. Save to Library. Create Alert. Launch Research Feed. Share This Paper. Topics from this paper.

References Publications referenced by this paper. An Med Mex. Cardiotoxicidad por Antraciclinas. Insuasty Insuasty Medicine Anticancer therapy induced cardiotoxicity: review of the literature.

Stemmler Medicine Anti-cancer drugs Prevention of Torsades de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. Related Papers. Abstract Topics 17 References Related Papers. By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy , Terms of Service , and Dataset License.

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Antraciclinas y síndrome QT prolongado adquirido. Presentación de un caso

Sudden death due to anthracycline-induced acute cardiotoxicity. ISSN Anthracyclines, such as doxorubicin, and monoclonal antibodies, such as trastuzumab, are compounds of wide clinical use as cytotoxic chemotherapy as they significantly reduce cancer-related mortality. However, the toxicity is a major adverse effect of these agents, which may occur at any time in their administration or afterwards, especially when used in combination. Cardiovascular toxicity by doxorubicin is dose-dependent and irreversible, while that caused by trastuzumab is not. Despite documented evidence of arrhythmias in both human and animal models, sudden cardiac death during or immediately after the infusion of chemotherapy is not well described.

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2014, Número 3

Anthracycline-mediated cardiomyopathy: Basic molecular knowledge for the cardiologist. E-mail address: jsalazar bellvitgehospital. Received April 25, Accepted August 20, Anthracyclines are cytostatic antibiotics discovered almost half a century ago exerting their action through inhibition of topoisomerase II. The two most representative drugs are doxorubicin and daunorubicin and they have been proven as useful antineoplastics and are widely prescribed in daily oncology practice; unfortunately, cardiotoxicity has been a limiting factor when it comes to their use. Diverse mechanisms have been involved in anthracycline cardiotoxicity, none of which are capable of causing the whole clinical picture by itself.

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